Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.49 |
| ▸ | GPR3 | P46089 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990655 | 0.95 | GRM2 (0.53) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL9751652 | 0.89 | GRM2 (0.43) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL8990631 | 0.88 | GRM2 (0.47) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL9737693 | 0.88 | GRM2 (0.47) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL9227374 | 0.86 | GRM2 (0.47) | GRM2ALOX5APFEN1S1PR1S1PR3 | |
| SCHEMBL9221140 | 0.85 | GRM2 (0.48) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL8990699 | 0.85 | RARB (0.49) | GRM2RARBFFAR4FDFT1HTR2A | |
| SCHEMBL9225207 | 0.84 | GRM2 (0.47) | GRM2GPR3ALOX5APFEN1S1PR1 | |
| SCHEMBL9221137 | 0.84 | RARB (0.50) | GRM2RARBFFAR4FDFT1HTR2A | |
| SCHEMBL3163945 | 0.81 | GRM2 (0.46) | GRM2GPR3ALOX5APFEN1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429558-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1991-06-05 | — | — | EP | disclosed |