Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663375 | 0.93 | RARB (0.51) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9399089 | 0.91 | HTR2A (0.52) | RARBRARARARGHSD17B10S1PR1 | |
| SCHEMBL9398851 | 0.91 | HTR2A (0.52) | RARBRARARARGHSD17B10S1PR1 | |
| SCHEMBL8990636 | 0.89 | MAOB (0.47) | RARBRARARARGHSD17B10HTR2A | |
| SCHEMBL8990815 | 0.89 | RARB (0.48) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9664166 | 0.88 | RARB (0.46) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9398566 | 0.88 | HTR2A (0.52) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9399279 | 0.87 | S1PR1 (0.51) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9796319 | 0.87 | RARB (0.47) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9663861 | 0.87 | RARB (0.58) | RARBRARARARGTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |