Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663375 | 0.95 | RARB (0.51) | RARBRARARARGS1PR1TSHR | |
| SCHEMBL9664336 | 0.94 | ALOX5 (0.41) | RARBRARARARGHSD17B10MAPT | |
| SCHEMBL9796319 | 0.93 | RARB (0.47) | RARBRARARARGS1PR1TSHR | |
| SCHEMBL12740165 | 0.90 | RARB (0.44) | RARBRARARARGS1PR1HSD11B1 | |
| SCHEMBL9663861 | 0.89 | RARB (0.58) | RARBRARARARGS1PR1TSHR | |
| SCHEMBL9664848 | 0.89 | TAAR1 (0.40) | RARBRARARARGHSD17B10MAPT | |
| SCHEMBL8990636 | 0.89 | MAOB (0.47) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL8990742 | 0.88 | RARB (0.50) | RARBRARARARGS1PR1TSHR | |
| SCHEMBL9664990 | 0.88 | RARB (0.60) | RARBRARARARGTSHRHSD17B10 | |
| SCHEMBL9664954 | 0.87 | RARB (0.47) | RARBRARARARGHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093026-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-03 | — | — | US | disclosed |