Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664336 | 0.95 | ALOX5 (0.41) | MAOBHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL9664848 | 0.90 | TAAR1 (0.40) | MAOBHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL8990742 | 0.89 | RARB (0.50) | MAOBHTR2AHTR2CALDH1A1RARB | |
| SCHEMBL9664166 | 0.89 | RARB (0.46) | HTR2AALOX5ALDH1A1RARBMAPT | |
| SCHEMBL9664954 | 0.88 | RARB (0.47) | MAOBHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL9663375 | 0.88 | RARB (0.51) | HTR2AHTR2CPTGS1PTGS2LMNA | |
| SCHEMBL8990876 | 0.88 | MAOB (0.45) | MAOBHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL8990724 | 0.85 | MAOB (0.50) | MAOBTAAR1 | |
| SCHEMBL8990619 | 0.84 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8990730 | 0.84 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |