Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990801 | 0.94 | GHSR (0.39) | GHSRAGTR1KCNA5TSHRMEN1 | |
| SCHEMBL8990997 | 0.93 | GHSR (0.40) | GHSRAGTR1 | |
| SCHEMBL8990923 | 0.92 | GHSR (0.47) | GHSRAGTR1 | |
| SCHEMBL8990759 | 0.91 | GHSR (0.48) | GHSRAGTR1 | |
| SCHEMBL8990751 | 0.91 | GHSR (0.47) | GHSRAGTR1MEN1KMT2A | |
| SCHEMBL8990858 | 0.88 | GHSR (0.43) | GHSRAGTR1KCNA5TSHRMEN1 | |
| SCHEMBL8990755 | 0.87 | GHSR (0.40) | GHSRAGTR1 | |
| SCHEMBL8990840 | 0.86 | GHSR (0.41) | GHSRAGTR1 | |
| SCHEMBL8990948 | 0.86 | GHSR (0.47) | GHSRAGTR1 | |
| SCHEMBL8991009 | 0.86 | GHSR (0.42) | GHSRKCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |