Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990886 | 0.92 | GHSR (0.50) | GHSRAGTR1TSHRBDKRB1MCHR1 | |
| SCHEMBL8990991 | 0.91 | GHSR (0.54) | GHSRAGTR1TSHRMCHR1HDAC1 | |
| SCHEMBL8990681 | 0.90 | GHSR (0.55) | GHSRAGTR1MCHR1HDAC1 | |
| SCHEMBL8990801 | 0.89 | GHSR (0.39) | GHSRAGTR1TSHRBDKRB1KMT2A | |
| SCHEMBL8990750 | 0.88 | GHSR (0.39) | GHSRAGTR1TSHRKMT2AKCNA5 | |
| SCHEMBL8991136 | 0.86 | GHSR (0.46) | GHSRAGTR1TSHRMCHR1 | |
| SCHEMBL8991065 | 0.86 | GHSR (0.39) | GHSRAGTR1TSHRMCL1HTR7 | |
| SCHEMBL8990979 | 0.83 | GHSR (0.51) | GHSRAGTR1KMT2AHDAC1KCNA5 | |
| SCHEMBL8990767 | 0.83 | GHSR (0.48) | GHSRAGTR1MCHR1KCNA5 | |
| SCHEMBL8990951 | 0.82 | GHSR (0.61) | GHSRAGTR1MCHR1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |