Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107587 | 0.94 | GHSR (0.59) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990927 | 0.94 | GHSR (0.58) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8991051 | 0.92 | GHSR (0.49) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8991128 | 0.90 | GHSR (0.68) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8991044 | 0.90 | GHSR (0.60) | GHSRTACR1OPRM1OPRD1MCHR1 | |
| SCHEMBL8990744 | 0.88 | GHSR (0.43) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990737 | 0.88 | GHSR (0.43) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990944 | 0.86 | GHSR (0.51) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990713 | 0.86 | GHSR (0.44) | GHSRTACR1AGTR2OPRM1OPRD1 | |
| SCHEMBL8990806 | 0.85 | GHSR (0.43) | GHSRTACR1AGTR2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |