Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | DRD3 | P35462 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107587 | 0.93 | GHSR (0.59) | GHSRAGTR1TACR1DRD2DRD4 | |
| SCHEMBL8990785 | 0.92 | GHSR (0.41) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990743 | 0.91 | GHSR (0.58) | GHSRAGTR1TACR1DRD2DRD4 | |
| SCHEMBL8990829 | 0.91 | GHSR (0.52) | GHSRAGTR1TACR1DRD2DRD4 | |
| SCHEMBL8991015 | 0.90 | GHSR (0.45) | GHSRAGTR1TACR1DRD2DRD4 | |
| SCHEMBL8990949 | 0.90 | GHSR (0.43) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990838 | 0.89 | GHSR (0.51) | GHSRAGTR1TACR1DRD2DRD4 | |
| SCHEMBL8990906 | 0.89 | GHSR (0.44) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990764 | 0.86 | GHSR (0.59) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990927 | 0.86 | GHSR (0.58) | GHSRAGTR1TACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |