Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 7/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687449 | 0.94 | MAOB (0.57) | MAOBTAAR1KIF11FDFT1CHKA | |
| SCHEMBL8990753 | 0.88 | MAOB (0.61) | MAOBTAAR1KIF11FDFT1DAO | |
| SCHEMBL91061 | 0.87 | TAAR1 (0.54) | MAOBTAAR1KIF11MIF | |
| SCHEMBL9809579 | 0.86 | MAOB (0.63) | MAOBTAAR1KIF11FDFT1DAO | |
| Ammonia Solution, Strong SCHEMBL266277 | 0.85 | TAAR1 (0.52) | MAOBTAAR1KIF11MIF | |
| SCHEMBL8990675 | 0.85 | MAOB (0.58) | MAOBTAAR1KIF11FDFT1DAO | |
| SCHEMBL8990601 | 0.83 | MAOB (0.56) | MAOBTAAR1FDFT1 | |
| SCHEMBL934227 | 0.82 | TAAR1 (0.73) | MAOBTAAR1DAOMIF | |
| SCHEMBL10381413 | 0.82 | MAOB (0.59) | MAOBTAAR1KIF11FDFT1 | |
| SCHEMBL31277159 | 0.81 | SRD5A2 (0.50) | MAOBTAAR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |