Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TXN | P10599 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15147441 | 0.89 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5026070 | 0.88 | ALDH1A1 (0.50) | HTTSMN1; SMN2L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL20672948 | 0.80 | SCN5A (0.35) | HTTSMN1; SMN2L3MBTL1KIF11 | |
| SCHEMBL10692096 | 0.76 | — | — | |
| SCHEMBL1103762 | 0.76 | — | — | |
| SCHEMBL6235346 | 0.75 | CYP3A4 (0.65) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL197675 | 0.73 | — | — | |
| SCHEMBL2580143 | 0.73 | — | — | |
| SCHEMBL1129102 | 0.73 | — | — | |
| SCHEMBL2154577 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722969-A1 | Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5175240-A | Using chlorinated aromatic diamine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0491306-A1 | Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4129678-A | POLYIMIDE, POLYAMIDEIMIDE OR POLYESTERIMIDE LAYER AND POLYVINYL FORMAL OR EPOXY RESIN LAYER | HITACHI, LTD. (JP) | 1978-12-12 | — | — | US | disclosed |