Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990880 | 0.92 | GHSR (0.42) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 | |
| SCHEMBL8990990 | 0.91 | GHSR (0.38) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 | |
| SCHEMBL8990793 | 0.90 | GHSR (0.38) | GHSRAGTR1HDAC1SMN1; SMN2KMT2A | |
| SCHEMBL8990947 | 0.90 | GHSR (0.38) | GHSRAGTR1HDAC1SMN1; SMN2KMT2A | |
| SCHEMBL8991018 | 0.88 | GHSR (0.35) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 | |
| SCHEMBL8990833 | 0.88 | GHSR (0.35) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 | |
| SCHEMBL8990991 | 0.88 | GHSR (0.54) | GHSRAGTR1HDAC1PTGER1PTGER3 | |
| SCHEMBL8990872 | 0.87 | GHSR (0.40) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 | |
| SCHEMBL8990897 | 0.86 | GHSR (0.47) | GHSRAGTR1HDAC1 | |
| SCHEMBL8990909 | 0.83 | GHSR (0.38) | GHSRAGTR1HDAC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |