Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990845 | 0.93 | GHSR (0.37) | GHSRAGTR1HDAC1KMT2ASIGMAR1 | |
| SCHEMBL8990990 | 0.90 | GHSR (0.38) | GHSRAGTR1HDAC1KMT2ASMN1; SMN2 | |
| SCHEMBL8990849 | 0.90 | GHSR (0.42) | GHSRAGTR1HDAC1KMT2ASMN1; SMN2 | |
| SCHEMBL8990875 | 0.90 | GHSR (0.31) | GHSRAGTR1 | |
| SCHEMBL8990788 | 0.89 | GHSR (0.47) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990749 | 0.89 | GHSR (0.31) | GHSR | |
| SCHEMBL8990947 | 0.89 | GHSR (0.38) | GHSRAGTR1HDAC1KMT2ASIGMAR1 | |
| SCHEMBL8991057 | 0.88 | GHSR (0.40) | GHSRAGTR1HDAC1KMT2ASIGMAR1 | |
| SCHEMBL8991082 | 0.87 | GHSR (0.41) | GHSRAGTR1HDAC1KMT2A | |
| SCHEMBL8990938 | 0.84 | GHSR (0.48) | GHSRAGTR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |