Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990869 | 1.00 | GHSR (0.40) | GHSRTAS1R3TAS1R1AGTR1AGTR2 | |
| SCHEMBL8990974 | 0.89 | GHSR (0.45) | GHSRAGTR1PPARGMEN1KMT2A | |
| SCHEMBL8990967 | 0.89 | GHSR (0.45) | GHSRAGTR1PPARGMEN1KMT2A | |
| SCHEMBL8991036 | 0.88 | GHSR (0.40) | GHSRAGTR1PPARGKMT2AHDAC1 | |
| SCHEMBL8991040 | 0.88 | GHSR (0.40) | GHSRAGTR1PPARGKMT2AHDAC1 | |
| SCHEMBL8990822 | 0.88 | GHSR (0.55) | GHSRMEN1KMT2A | |
| SCHEMBL8990924 | 0.85 | GHSR (0.45) | GHSRMEN1KMT2A | |
| SCHEMBL8990821 | 0.84 | GHSR (0.54) | GHSRMEN1KMT2A | |
| SCHEMBL8991154 | 0.84 | TAS1R3 (0.32) | TAS1R3TAS1R1AGTR1AGTR2PPARG | |
| SCHEMBL8990929 | 0.83 | GHSR (0.55) | GHSRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |