Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990939 | 0.92 | GHSR (0.68) | GHSRTACR1OPRM1OPRD1MME | |
| SCHEMBL8990958 | 0.85 | GHSR (0.61) | GHSRTACR1OPRM1DRD2DRD4 | |
| SCHEMBL8991128 | 0.84 | GHSR (0.68) | GHSRTACR1OPRM1OPRD1MME | |
| SCHEMBL8990827 | 0.84 | GHSR (0.59) | GHSRTACR1DRD2DRD4DRD3 | |
| SCHEMBL9107587 | 0.84 | GHSR (0.59) | GHSRTACR1OPRM1OPRD1DRD2 | |
| SCHEMBL8990816 | 0.83 | GHSR (0.68) | GHSRTACR1OPRM1OPRD1MME | |
| SCHEMBL8990743 | 0.83 | GHSR (0.58) | GHSRTACR1OPRM1OPRD1MME | |
| SCHEMBL8991054 | 0.82 | GHSR (0.56) | GHSRTACR1OPRM1OPRD1MME | |
| SCHEMBL8990879 | 0.80 | GHSR (0.52) | GHSRTACR1OPRM1OPRD1HDAC1 | |
| SCHEMBL8991005 | 0.80 | GHSR (0.55) | GHSRTACR1OPRM1OPRD1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |