Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991119 | 1.00 | GHSR (0.42) | GHSRNAMPTHRH4MMEACE | |
| SCHEMBL8991005 | 0.83 | GHSR (0.55) | GHSRNAMPTHRH4MMEACE | |
| SCHEMBL8990790 | 0.81 | GHSR (0.54) | GHSRNAMPTHRH4MMEACE | |
| SCHEMBL8991136 | 0.81 | GHSR (0.46) | GHSRNAMPTHRH4MMEACE | |
| SCHEMBL8990794 | 0.80 | HRH4 (0.43) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL8990800 | 0.80 | HRH4 (0.43) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL7794388 | 0.80 | GHSR (0.64) | GHSRACEPTGER1PTGER4PTGER3 | |
| SCHEMBL7794392 | 0.80 | GHSR (0.64) | GHSRACEPTGER1PTGER4PTGER3 | |
| SCHEMBL8991054 | 0.79 | GHSR (0.56) | GHSRHRH4MMEACEOPRM1 | |
| SCHEMBL8990816 | 0.78 | GHSR (0.68) | GHSRHRH4MMEACEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |