Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990800 | 1.00 | HRH4 (0.43) | HRH4CTSLCTSBMMEACE | |
| SCHEMBL8991003 | 0.84 | GHSR (0.51) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL8990897 | 0.82 | GHSR (0.47) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL8990820 | 0.81 | HDAC1 (0.43) | OPRM1OPRD1PTGER1PTGER4PTGER3 | |
| SCHEMBL8990811 | 0.81 | HDAC1 (0.43) | OPRM1OPRD1PTGER1PTGER4PTGER3 | |
| SCHEMBL8991113 | 0.80 | GHSR (0.42) | HRH4CTSLCTSBMMEACE | |
| SCHEMBL8991119 | 0.80 | GHSR (0.42) | HRH4CTSLCTSBMMEACE | |
| SCHEMBL8991127 | 0.78 | MME (0.36) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL8991035 | 0.77 | MME (0.36) | HRH4MMEACEOPRM1OPRD1 | |
| SCHEMBL8990865 | 0.77 | GHSR (0.44) | PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |