Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991300 | 0.89 | PDE4A (0.43) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991058 | 0.85 | MAPK1 (0.55) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991261 | 0.82 | KDM4E (0.49) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991162 | 0.82 | KDM4E (0.46) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991491 | 0.80 | HTT (0.42) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991480 | 0.79 | KDM4E (0.44) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991123 | 0.79 | KDM4E (0.44) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991256 | 0.78 | KDM4E (0.40) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991284 | 0.77 | KDM4E (0.44) | HTTKDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL8991379 | 0.77 | KDM4E (0.44) | HTTKDM4ETSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |