Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991066 | 0.89 | ALDH1A1 (0.44) | KDM4EHSD17B10MAPK1HTTALDH1A1 | |
| SCHEMBL8991261 | 0.88 | KDM4E (0.49) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991058 | 0.87 | MAPK1 (0.55) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991379 | 0.85 | KDM4E (0.44) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991022 | 0.81 | KDM4E (0.44) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991162 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991011 | 0.80 | KDM4E (0.49) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991267 | 0.79 | KDM4E (0.48) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991091 | 0.79 | EGFR (0.43) | HPGDEGFRPDE8BSRCABL1 | |
| SCHEMBL8991133 | 0.77 | HTT (0.45) | KDM4EHSD17B10MAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |