Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991103 | 0.88 | PDE4A (0.50) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991231 | 0.87 | GAA (0.41) | MAPTTP53PDE4APDE4BPDE4C | |
| SCHEMBL7697684 | 0.86 | ADRA1D (0.41) | MAPTTP53ADRA1DALDH1A1CYP11B1 | |
| SCHEMBL8991412 | 0.81 | PDE4A (0.42) | AURKARPS6KB1PDE4APDE4BPDE4C | |
| SCHEMBL8991264 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DYTHDC1 | |
| SCHEMBL8991207 | 0.81 | AURKA (0.40) | MAPTTP53AURKARPS6KB1PDE4A | |
| SCHEMBL8991221 | 0.79 | MEN1 (0.39) | MAPTTP53AURKARPS6KB1PDE4A | |
| SCHEMBL8991365 | 0.77 | ADORA2A (0.41) | MAPTAURKARPS6KB1PDE4APDE4B | |
| SCHEMBL8991388 | 0.77 | PDE4A (0.50) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991063 | 0.76 | GAA (0.41) | MAPTTP53PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |