Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991110 | 0.89 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL8991244 | 0.88 | PDE4A (0.40) | MAPTTP53PDE4APDE4BPDE4C | |
| SCHEMBL7697687 | 0.87 | RIPK1 (0.42) | AURKAMAPTTP53ADRA1DNPC1 | |
| SCHEMBL8991419 | 0.82 | PDE4A (0.40) | AURKARPS6KB1MAPTPDE4APDE4B | |
| SCHEMBL8991238 | 0.81 | AURKA (0.40) | AURKARPS6KB1MAPTPDE4APDE4B | |
| SCHEMBL8991272 | 0.81 | PDE4A (0.38) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991194 | 0.81 | MAPT (0.41) | AURKARPS6KB1MAPTTP53PDE4A | |
| SCHEMBL8991378 | 0.78 | ADORA2A (0.41) | AURKARPS6KB1MAPTPDE4APDE4B | |
| SCHEMBL7700322 | 0.75 | ADK (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7698505 | 0.74 | FYN (0.39) | RPS6KB1MAPTTP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |