Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991380 | 0.89 | KDM1A (0.35) | — | |
| SCHEMBL7495764 | 0.86 | NPSR1 (0.37) | POLBMAPTNPSR1MEN1KMT2A | |
| SCHEMBL8991007 | 0.80 | — | — | |
| SCHEMBL8991282 | 0.79 | — | — | |
| SCHEMBL8991174 | 0.77 | CYP19A1 (0.30) | — | |
| SCHEMBL7497849 | 0.75 | KDM1A (0.38) | POLBMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL8991475 | 0.67 | CYP19A1 (0.39) | — | |
| SCHEMBL7499785 | 0.64 | OPRM1 (0.36) | NPSR1CYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL7498327 | 0.63 | OPRM1 (0.35) | POLBNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL8991195 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504106-A | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |