Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886904 | 1.00 | CTSL (0.50) | CTSLCTSSCTSKKMT2AMEN1 | |
| SCHEMBL10896800 | 1.00 | CTSL (0.50) | CTSLCTSSCTSKKMT2AMEN1 | |
| SCHEMBL10896823 | 1.00 | CTSL (0.50) | CTSLCTSSCTSKKMT2AMEN1 | |
| SCHEMBL10885661 | 1.00 | CTSL (0.50) | CTSLCTSSCTSKKMT2AMEN1 | |
| SCHEMBL9443858 | 0.89 | KMT2A (0.43) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL10546982 | 0.88 | KMT2A (0.43) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL10540946 | 0.88 | KMT2A (0.43) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL10972137 | 0.88 | KMT2A (0.43) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL11203776 | 0.86 | CTSL (0.51) | CTSLCTSSCTSKKMT2AMEN1 | |
| SCHEMBL10889192 | 0.81 | CTSL (0.55) | CTSLCTSSCTSKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419215-B1 | Process for preparing 4-substituted azetidinones | LILLY CO ELI (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5106475-A | Alkylating, deprotecting, electrolytic reduction; intermediate for beta-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0419215-A2 | Process for preparing 4-substituted azetidinones | ELI LILLY AND COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |
| EP-0080942-B1 | NOVEL INTERMEDIATES AND PROCESS FOR PREPARING (S)-3-ACYLAMINO-4-SUBSTITUTED-2-AZETIDINONES | E.R. Squibb & Sons, Inc. (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4421686-A | 4-Norbornyl-sulfonyl azetidinone intermediates and process for preparing (S)-3-acylamino-4-substituted-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0080942-A1 | Novel intermediates and process for preparing (S)-3-acylamino-4-substituted-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1983-06-08 | — | — | EP | disclosed |