Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.74 |
| ▸ | RELA | Q04206 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357205 | 0.83 | MAPT (0.59) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8357739 | 0.83 | MAPT (0.62) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6635501 | 0.83 | MAPT (0.67) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3077568 | 0.82 | CYP1A2 (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL617400 | 0.79 | KEAP1 (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1060971 | 0.78 | CYP1A2 (0.67) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8361473 | 0.78 | MAPT (0.80) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9042870 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL865987 | 0.76 | KEAP1 (0.74) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8991608 | 0.76 | MAPT (0.55) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529998-A | ANTIBACTERIAL MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0697412-A1 | Benzoxazolyl- and benzo-thiazolyl-oxazolidinones | BAYER AG (DE) | 1996-02-21 | — | — | EP | disclosed |