Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943133 | 0.74 | MGAM (0.48) | LMNAALDH1A1HSD17B10 | |
| SCHEMBL16994943 | 0.73 | — | — | |
| SCHEMBL7172284 | 0.73 | — | — | |
| SCHEMBL156206 | 0.68 | — | — | |
| SCHEMBL9188326 | 0.68 | ALDH1A1 (0.32) | LMNAALDH1A1HSD17B10 | |
| SCHEMBL17658938 | 0.67 | — | — | |
| SCHEMBL28698674 | 0.67 | — | — | |
| SCHEMBL14408316 | 0.67 | TDP1 (0.41) | LMNAALDH1A1THRB | |
| SCHEMBL14957090 | 0.67 | — | — | |
| SCHEMBL223178 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722725-A1 | VASCULAR SMOOTH MUSCLE CELL MIGRATION INHIBITOR | TEIJIN LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |