Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | RAD52 | P43351 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | ACP1 | P24666 | 1/20 | 0.62 |
| ▸ | TOP2A | P11388 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23029669 | 0.92 | NCF1 (0.84) | NCF1SLC2A1CYP2C19POLBRAD52 | |
| SCHEMBL4632937 | 0.85 | NCF1 (0.73) | NCF1SLC2A1CYP2C19POLBRAD52 | |
| Quindecamine SCHEMBL2111177 | 0.83 | CYP2C19 (0.73) | NCF1SLC2A1CYP2C19OPRK1 | |
| SCHEMBL22390054 | 0.83 | CYP2C19 (0.73) | NCF1SLC2A1CYP2C19OPRK1 | |
| SCHEMBL12402667 | 0.83 | SLC2A1 (1.00) | NCF1SLC2A1POLBRAD52KDM4E | |
| SCHEMBL899224 | 0.82 | CYP2C19 (0.71) | NCF1CYP2C19OPRK1 | |
| SCHEMBL5436954 | 0.82 | CYP2C19 (0.97) | NCF1CYP2C19POLBRAD52KDM4E | |
| SCHEMBL5446310 | 0.82 | CYP2C19 (0.71) | NCF1CYP2C19OPRK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8686028 | 0.81 | CYP2C19 (1.00) | NCF1CYP2C19POLBRAD52KDM4E | |
| SCHEMBL18290253 | 0.81 | NCF1 (0.81) | NCF1CYP2C19OPRK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081211-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| US-9938525-B2 | Compositions and methods for selective delivery of oligonucleotide molecules to cell types | NLIFE THERAPEUTICS, S.L. (ES) | 2018-04-10 | — | — | US | disclosed |
| US-20150315575-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO CELL TYPES | PALOMO LIMITED (CY) | 2015-11-05 | — | — | US | disclosed |
| EP-2621903-A1 | N-HETEROARYL COMPOUNDS | Intervet International B.V. (NL) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041873-A1 | N-HETEROARYL COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315575-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO CELL TYPES | MSR1, HAVCR2, SNRPE | NCF1 795/4885SLC2A1 177/4885CYP2C19 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.