Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | NCF1 | P14598 | 5/20 | 0.69 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL899167 | 0.90 | CYP2C19 (0.70) | CYP2C19NCF1OPRK1NQO2 | |
| SCHEMBL11934982 | 0.88 | CYP2C19 (0.64) | CYP2C19NCF1OPRK1NQO2 | |
| Quindecamine SCHEMBL2111177 | 0.86 | CYP2C19 (0.73) | CYP2C19NCF1OPRK1NQO2 | |
| SCHEMBL22390054 | 0.86 | CYP2C19 (0.73) | CYP2C19NCF1OPRK1NQO2 | |
| SCHEMBL5446310 | 0.84 | CYP2C19 (0.71) | CYP2C19NCF1OPRK1NQO2 | |
| SCHEMBL5436954 | 0.84 | CYP2C19 (0.97) | CYP2C19NCF1OPRK1 | |
| Hydrochloric Acid SCHEMBL8686028 | 0.83 | CYP2C19 (1.00) | CYP2C19NCF1OPRK1 | |
| SCHEMBL7500041 | 0.83 | CYP2C19 (0.69) | CYP2C19NCF1OPRK1 | |
| SCHEMBL18290253 | 0.83 | NCF1 (0.81) | CYP2C19NCF1OPRK1NQO2 | |
| SCHEMBL23015234 | 0.82 | CYP2C19 (0.64) | CYP2C19NCF1OPRK1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621903-B1 | N-HETEROARYL COMPOUNDS | INTERVET INT BV (NL) | 2017-03-01 | — | — | EP | disclosed |
| US-8877934-B2 | N-heteroaryl compounds | INTERVET INC. (US) | 2014-11-04 | — | — | US | disclosed |
| EP-2621903-A1 | N-HETEROARYL COMPOUNDS | Intervet International B.V. (NL) | 2013-08-07 | — | — | EP | disclosed |
| US-20130196993-A1 | N-HETEROARYL COMPOUNDS | INTERVET INC. | 2013-08-01 | — | — | US | disclosed |
| WO-2012041873-A1 | N-HETEROARYL COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
| US-4608383-A | Cardioactive pyrazole and imidazole aryloxypropanolamines | BOEHRINGER MANNHEIM GMBH (DE) | 1986-08-26 | — | — | US | disclosed |
| US-4438128-A | ADRENERGIC BLOCKERS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196993-A1 | N-HETEROARYL COMPOUNDS | HNMT, SQLE, PIGO | CYP2C19 150/4885NCF1 681/4885FERMT2 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.