Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 15/20 | 0.64 |
| ▸ | CTSL | P07711 | 3/20 | 0.59 |
| ▸ | CTSS | P25774 | 3/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.59 |
| ▸ | CTSH | P09668 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232032 | 0.95 | CXCR4 (0.63) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL29533141 | 0.95 | CXCR4 (0.64) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL29366767 | 0.86 | CXCR4 (0.59) | CXCR4CXCL8 | |
| SCHEMBL31452901 | 0.86 | CXCR4 (0.67) | CXCR4CXCL8 | |
| SCHEMBL31683258 | 0.85 | CXCR4 (0.71) | CXCR4CXCL8 | |
| SCHEMBL1518999 | 0.84 | CXCR4 (0.60) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL31011012 | 0.84 | CXCR4 (0.68) | CXCR4CXCL8 | |
| SCHEMBL30285072 | 0.83 | CXCR4 (0.60) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL31433225 | 0.83 | CXCR4 (0.65) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL31482415 | 0.82 | CXCR4 (0.56) | CXCR4CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102708-B2 | Methods for the synthesis of dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2015-08-11 | — | — | US | disclosed |
| US-8759480-B2 | Contoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides | SYNGENE LIMITED (AU) | 2014-06-24 | — | — | US | disclosed |
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | SYNGENE LIMITED (AU) | 2013-05-16 | — | — | US | disclosed |
| US-20120142892-A1 | CONTOXIN ANALOGUES AND METHODS FOR SYNTHESIS OF INTRAMOLECULAR DICARBA BRIDGE-CONTAINING PEPTIDES | POLYCHIP PHARMACEUTICALS PTY LTD. (AU) | 2012-06-07 | — | — | US | disclosed |
| US-8188217-B2 | — | — | 2012-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | OTC, NBAS, IDH2 | CXCR4 3163/4885CTSL 3774/4885CTSS 3094/4885 |
| US-20120142892-A1 | CONTOXIN ANALOGUES AND METHODS FOR SYNTHESIS OF INTRAMOLECULAR DICARBA BRIDGE-CONTAINING PEPTIDES | VIP, CANX, INHA | CXCR4 1216/4885CTSL 675/4885CTSS 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.