SCHEMBL29533141

SCHEMBL29533141

C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CXCR4 P61073 15/20 0.64
▸ CTSL P07711 3/20 0.58
▸ CTSS P25774 3/20 0.58
▸ CTSK P43235 3/20 0.58
▸ CTSH P09668 1/20 0.58
▸ CXCL8 P10145 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991592 0.95 CXCR4 (0.64) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL29366767 0.91 CXCR4 (0.59) CXCR4CXCL8
SCHEMBL17232032 0.90 CXCR4 (0.63) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL30285072 0.88 CXCR4 (0.60) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL31154425 0.86 CXCR4 (0.65) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL30284926 0.86 CXCR4 (0.59) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL31452901 0.85 CXCR4 (0.67) CXCR4CXCL8
SCHEMBL29700788 0.84 CXCR4 (0.67) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL29532761 0.84 CCKBR (0.60) CXCR4
SCHEMBL31433225 0.84 CXCR4 (0.65) CXCR4CTSLCTSSCTSKCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2025-01-23 — — US disclosed
US-12162956-B2 Peptides and methods for reducing skin pigmentation GLO PHARMA, INC. (US) 2024-12-10 — — US disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
EP-4419126-A1 PHOTOACTIVATABLE ION CHANNEL MODULATOR Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2024-08-28 — — EP disclosed
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2024-06-13 — — US disclosed
US-20230303984-A1 Enzymes for Sialylation of Glycans MOMENTA PHARMACEUTICALS, INC. 2023-09-28 — — US disclosed
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation UNIVERSITY OF WINDSOR (CA) 2023-09-05 — — US disclosed
EP-4198029-A1 INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF University Health Network (CA) 2023-06-21 — — EP disclosed
WO-2023067366-A1 PHOTOACTIVATABLE ION CHANNEL MODULATOR INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-04-27 — — WO disclosed
CN-115605230-A Enzymes for sialylation of glycans 动量制药公司(US) 2023-01-13 — — CN disclosed
EP-4110391-A1 ENZYMES FOR SIALYLATION OF GLYCANS Momenta Pharmaceuticals, Inc. (US) 2023-01-04 — — EP disclosed
CN-110981967-B Dimer of alpha-conotoxin Mr1.1, synthetic method and application 中国海洋大学 2022-10-14 — — CN disclosed
EP-3337791-B1 INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF UNIV HEALTH NETWORK (CA) 2022-08-03 — — EP disclosed
US-20220153749-A1 Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation UNIVERSITY OF WINDSOR (CA) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153749-A1 Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation PTMS, CTH, VIP CXCR4 3046/4885CTSL 1778/4885CTSS 2269/4885
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R CXCR4 3150/4885CTSL 1535/4885CTSS 2514/4885
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation PTMS, CTH, VIP CXCR4 3046/4885CTSL 1778/4885CTSS 2269/4885
US-12162956-B2 Peptides and methods for reducing skin pigmentation MC1R, TYR, MC5R CXCR4 3150/4885CTSL 1535/4885CTSS 2514/4885
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R CXCR4 3150/4885CTSL 1535/4885CTSS 2514/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR CXCR4 1234/4885CTSL 217/4885CTSS 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback