SCHEMBL8991894

SCHEMBL8991894

CCCCCCCCCCC(=O)Nc1ccc(-c2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TUBB4A P04350 2/20 0.57
TUBB P07437 2/20 0.57
TUBA3C P0DPH7 2/20 0.57
TUBA1B P68363 2/20 0.57
TUBA4A P68366 2/20 0.57
TUBB4B P68371 2/20 0.57
TUBB3 Q13509 2/20 0.57
TUBB2A Q13885 2/20 0.57
TUBB8 Q3ZCM7 2/20 0.57
TUBA3E Q6PEY2 2/20 0.57
TUBA1A Q71U36 2/20 0.57
TUBA1C Q9BQE3 2/20 0.57
TUBB6 Q9BUF5 2/20 0.57
TUBB2B Q9BVA1 2/20 0.57
TUBB1 Q9H4B7 2/20 0.57
HDAC1 Q13547 4/20 0.56
HDAC2 Q92769 4/20 0.56
HDAC3 O15379 3/20 0.55
HDAC4 P56524 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11694913 0.85 HDAC8 (0.75) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7340472 0.81 THRA (0.53) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7335188 0.81 THRA (0.53) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21998749 0.81 MEN1 (0.66) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21998667 0.81 MEN1 (0.66) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21999373 0.81 MEN1 (0.66) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL10933021 0.81 KMT2A (0.59) ALDH1A1MAPTNPC1LMNARAB9A
SCHEMBL7337841 0.80 THRA (0.54) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL10067549 0.79 TP53 (0.61) ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5319266 0.79 HDAC3 (0.72) ALDH1A1HDAC1HDAC2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592269-B1 Antiferroelectric liquid crystal compound and liquid crystal composition containing the same SHOWA SHELL SEKIYU (JP) 1996-07-24 EP disclosed
EP-0592269-A1 Antiferroelectric liquid crystal compound and liquid crystal composition containing the same Showa Shell Sekiyu Kabushiki Kaisha (JP) 1994-04-13 EP disclosed