Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335188 | 1.00 | THRA (0.53) | THRATHRBCNR1SMN1; SMN2NPC1 | |
| SCHEMBL7337841 | 0.99 | THRA (0.54) | THRATHRBCNR1SMN1; SMN2NPC1 | |
| SCHEMBL7337979 | 0.95 | ALDH1A1 (0.54) | THRATHRBSMN1; SMN2NPC1LMNA | |
| SCHEMBL7337493 | 0.90 | KMT2A (0.52) | THRBSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL7328819 | 0.85 | KMT2A (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11330880 | 0.82 | POLB (0.51) | THRATHRBCNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7336971 | 0.82 | EPHX1 (0.56) | LMNAALDH1A1HTTEPHX2 | |
| SCHEMBL8991894 | 0.81 | ALDH1A1 (0.57) | THRBSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL7333599 | 0.81 | HDAC1 (0.53) | CNR1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL7333819 | 0.81 | RAB9A (0.67) | THRBSMN1; SMN2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |