Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784738 | 0.82 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL28829696 | 0.80 | LMNA (0.55) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632691 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632701 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632748 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632726 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11515161 | 0.76 | GAA (0.53) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632704 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL782902 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL31632753 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719250-A1 | SYNTHESIS OF AMIDO ACIDS FROM CARBOXYLIC ACIDS AND LACTAMS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |