Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GALR2 | O43603 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738072 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL3481205 | 0.85 | TSHR (0.64) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL1523174 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL7860227 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL11464655 | 0.84 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL1611630 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL22391679 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL960443 | 0.83 | TSHR (0.53) | ALDH1A1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL4135400 | 0.82 | THRB (0.55) | ALDH1A1SMN1; SMN2GAATSHRMAPT | |
| SCHEMBL5752237 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GAATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105340-A | Benzamide and nicotinamide compounds and its application method | 昂康塔睿迪斯股份有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-110016015-A | Benzamide and nicotinamide compounds and its application method | 昂康塔睿迪斯股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-104640846-A | Benzimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI SA | 2015-05-20 | — | — | CN | disclosed |
| US-5543550-A | NITRATING ALKYL ESTER OF 3-FLUOROBENZOIC ACID DISSOLVED IN SOLVENT-FREE SULFURIC ACID, THEN ADDING WATER, SEPARATION, HYDROLYSIS, PRESSURIZED CATALYTIC HYDROGENATION OF THE NITRATED ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |