Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15275513 | 0.87 | LMNA (0.48) | HPGDSMN1; SMN2GAAFAAHMGLL | |
| SCHEMBL8882738 | 0.83 | HPGD (0.49) | HPGDSMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL10420577 | 0.80 | PHGDH (0.51) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL8992020 | 0.80 | PHGDH (0.51) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL8992021 | 0.80 | PHGDH (0.51) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL8883608 | 0.80 | FKBP1A (0.48) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL8882749 | 0.78 | SMN1; SMN2 (0.59) | HPGDTSHRSMN1; SMN2GAARAB9A | |
| SCHEMBL15275509 | 0.78 | SMN1; SMN2 (0.39) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL15275508 | 0.77 | MAPT (0.46) | HPGDTSHRSMN1; SMN2GAAFAAH | |
| SCHEMBL8884084 | 0.76 | RAB9A (0.53) | PHGDHHPGDTSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068335-A2 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2012-05-24 | — | — | WO | disclosed |