Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824410 | 0.84 | NR1I2 (0.35) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8824405 | 0.84 | NPC1 (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8603712 | 0.81 | NR1I2 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL9078729 | 0.78 | RAB9A (0.41) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8551728 | 0.78 | NR1I2 (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553780 | 0.77 | NPC1 (0.36) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8824428 | 0.76 | NR1I2 (0.39) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553801 | 0.76 | NR1I2 (0.35) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8556856 | 0.76 | NR1I2 (0.33) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8605399 | 0.76 | NR1I2 (0.36) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514679-A | TREATMENT OF PICORNAVIRUS INFECTIONS | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |