Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992186 | 0.85 | CYP1A2 (0.37) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8992351 | 0.83 | CYP1A2 (0.36) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16210474 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16210472 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16209808 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16209749 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16209748 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16209810 | 0.78 | SOAT2 (0.44) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16210098 | 0.75 | SOAT2 (0.42) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 | |
| SCHEMBL16209644 | 0.75 | SOAT2 (0.42) | TSHRCYP3A4ALDH1A1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |