SCHEMBL16209644

SCHEMBL16209644

CCCCCCCCCCC=C[SiH](CCCCCCCCCCCCCC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
EPHX2 P34913 4/20 0.40
FAAH O00519 2/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
F7 P08709 4/20 0.37
F3 P13726 4/20 0.37
MMP2 P08253 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 1/20 0.37
ECE1 P42892 1/20 0.37
SGMS1 Q86VZ5 1/20 0.37
SGMS2 Q8NHU3 1/20 0.37
MUS81 Q96NY9 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
ALDH1A1 P00352 3/20 0.37
DUSP3 P51452 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16210097 1.00 SOAT2 (0.42) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16210098 1.00 SOAT2 (0.42) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16209643 1.00 SOAT2 (0.42) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16209808 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16209749 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16210472 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16210474 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16209810 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL16209748 0.83 SOAT2 (0.44) SOAT2SOAT1EPHX2FAAHCNR1
SCHEMBL8992168 0.75 CYP1A2 (0.37) SOAT2SOAT1EPHX2FAAHCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2994474-B1 SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION MOMENTIVE PERFORMANCE MAT INC (US) 2017-12-20 EP disclosed
US-9371339-B2 Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-06-21 US disclosed
EP-2994474-A1 SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION Momentive Performance Materials Inc. (US) 2016-03-16 EP disclosed
US-20140330036-A1 SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION PRINCETON UNIVERSITY (US) 2014-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140330036-A1 SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION YAP1, LATS1, SIK1 SOAT2 1226/4885SOAT1 1429/4885EPHX2 4149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.