Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157744 | 0.88 | FFAR1 (0.53) | PPARGPPARAPTPN1TP53POLB | |
| SCHEMBL9260216 | 0.81 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2PTPN1 | |
| SCHEMBL5759859 | 0.80 | PPARG (0.63) | PPARGPPARAPTPN1 | |
| SCHEMBL8545784 | 0.79 | PPARG (0.55) | PPARGPPARACYP2C9KCNH2PTPN1 | |
| SCHEMBL6972900 | 0.79 | CDK4 (0.56) | PPARGPPARAPTPN1TP53POLB | |
| SCHEMBL6972899 | 0.79 | CDK4 (0.56) | PPARGPPARAPTPN1TP53POLB | |
| SCHEMBL9092427 | 0.78 | PPARG (0.45) | PPARGPPARAPOLB | |
| SCHEMBL7897429 | 0.78 | PPARG (0.61) | PPARGPPARAPTPN1 | |
| SCHEMBL27636490 | 0.77 | TP53 (0.56) | PPARGPPARACYP2C9KCNH2PTPN1 | |
| SCHEMBL8799608 | 0.76 | PPARG (0.61) | PPARGPPARACYP2C9KCNH2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510360-A | ADMINISTERING ORALLY, SIDE EFFECT REDUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| US-5504097-A | TREATING ATHEROSCLEROSIS BY ADMINISTERING AN ANTILIPEMIC OR ANTICHOLESTEROL AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-02 | — | — | US | disclosed |