SCHEMBL8992256

SCHEMBL8992256

CC(C)NC1C=CC(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAOB P27338 4/20 0.32
MAOA P21397 3/20 0.32
ALDH1A1 P00352 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992438 0.91 SLC6A2 (0.34) ALDH1A1
Hydrochloric Acid SCHEMBL8992580 0.79 HTR2A (0.39) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL8992275 0.77 MAOB (0.32) MAOBMAOAHTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL8992323 0.75 MAOB (0.33) MAOBMAOAHTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL8992591 0.75 HTR2A (0.36) MAOBMAOAALDH1A1HTR2AHTR2C
Hydrochloric Acid SCHEMBL8992368 0.71 KDM1A (0.36) MAOBMAOA
Hydrochloric Acid SCHEMBL8992422 0.71 OPRM1 (0.43) MAOA
Hydrochloric Acid SCHEMBL8992469 0.71 SLC6A2 (0.40) MAOBALDH1A1HTR2AHTR2CHTR2B
SCHEMBL8992324 0.70 ATM (0.32) MAOB
SCHEMBL8992355 0.67 MAOB (0.38) GAAMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445749-B1 N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments FUJISAWA PHARMACEUTICAL CO (JP) 1996-07-10 EP disclosed
US-5256824-A Anticholinergic agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-26 US disclosed
EP-0445749-A1 N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-09-11 EP disclosed