Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725607 | 0.74 | SLC22A1 (0.48) | KMT2ATSHRPOLBMEN1HTT | |
| SCHEMBL8992280 | 0.69 | HDAC4 (0.36) | HDAC4GAAALDH1A1 | |
| SCHEMBL11730235 | 0.68 | SLC22A1 (0.66) | OPRM1SLC22A1 | |
| SCHEMBL11803731 | 0.66 | NPSR1 (0.39) | KMT2ATSHRGAAALDH1A1OPRM1 | |
| SCHEMBL10448804 | 0.66 | GAA (0.35) | KMT2ATSHRPOLBMEN1HTT | |
| SCHEMBL10448813 | 0.64 | TSHR (0.43) | KMT2ATSHRGAAALDH1A1OPRM1 | |
| SCHEMBL11884873 | 0.64 | KDM4E (0.40) | KMT2ATSHRPOLBMEN1HTT | |
| SCHEMBL9047574 | 0.62 | HTT (0.41) | KMT2ATSHRPOLBMEN1HTT | |
| SCHEMBL11593041 | 0.61 | ALDH1A1 (0.50) | KMT2APOLBMEN1HTTLMNA | |
| SCHEMBL5376177 | 0.61 | HDAC4 (0.62) | KMT2AMEN1HDAC4HTTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |