Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683226 | 0.71 | HTR1A (0.33) | HTR1AMAOBMAOAGAAALDH1A1 | |
| SCHEMBL8992376 | 0.69 | KMT2A (0.39) | HDAC4GAAALDH1A1 | |
| SCHEMBL10700596 | 0.67 | SMN1; SMN2 (0.37) | ALDH1A1 | |
| SCHEMBL22436648 | 0.65 | HTR1A (0.44) | HTR1AMAOBMAOA | |
| SCHEMBL7587503 | 0.64 | HTR1A (0.46) | HTR1AGAA | |
| SCHEMBL23198926 | 0.62 | AKR1C1 (0.39) | HTR1A | |
| SCHEMBL28249690 | 0.62 | AKR1C1 (0.39) | HTR1A | |
| SCHEMBL28248386 | 0.62 | AKR1C1 (0.39) | HTR1A | |
| SCHEMBL28580198 | 0.62 | ALOX5AP (0.34) | HTR1AGAAALDH1A1 | |
| SCHEMBL170243 | 0.61 | SLC18A3 (0.45) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |