Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949712 | 0.87 | GRM5 (0.35) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3952813 | 0.84 | GRM5 (0.41) | GRM5NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4950469 | 0.80 | APP (0.44) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3885779 | 0.80 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL563613 | 0.80 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10606190 | 0.80 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3952763 | 0.78 | GRM5 (0.36) | GRM5CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Diphenylacetylene SCHEMBL3842452 | 0.78 | APP (0.60) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6564060 | 0.77 | APP (0.46) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6564353 | 0.77 | APP (0.46) | APPGRM5NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1709928-A | Aryne resin containing silicone | UNIV HUADONG TECHNOLOGY (CN) | 2005-12-21 | — | — | CN | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5306445-A | Porous substrate loaded with phosphor | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5240647-A | Surface treatment of silica aerogel with tritium gas; phosphor emitter; batteries | ASHLEY CAROL S (US) | 1993-08-31 | — | — | US | disclosed |
| US-5137659-A | Porous substrate, source of exciting radiation, activable component | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1992-08-11 | — | — | US | disclosed |
| US-5122305-A | Aerogel substrate loaded with composite of carrier and radiation source or emitter | UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF ENERGY | 1992-06-16 | — | — | US | disclosed |
| US-5078919-A | Solid-State Radioluminescent Compositions And Devices | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1992-01-07 | — | — | US | disclosed |