Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992379 | 0.80 | APP (0.50) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL9011423 | 0.78 | APP (0.48) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL31387703 | 0.78 | APP (0.48) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL10606190 | 0.70 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3885779 | 0.70 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL563613 | 0.70 | APP (0.55) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6562608 | 0.69 | APP (0.42) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL6563926 | 0.69 | APP (0.42) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL6564255 | 0.69 | APP (0.42) | APPHTR2AGRM5NPC1RAB9A | |
| SCHEMBL26104862 | 0.69 | APP (0.61) | APPGRM5NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319129-B2 | Silsesquioxane derivative and process for producing the same | CHISSO CORPORATION (JP) | 2008-01-15 | — | — | US | disclosed |
| US-7053167-B2 | Silsesquioxane derivative having functional group | CHISSO CORPORATION (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | ITO KENYA | 2006-04-27 | — | — | US | disclosed |
| US-20060052623-A1 | Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance | CHISSO CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| US-20040068074-A1 | Production process for silsesquioxane derivative having functional group and silsesquioxane derivative | JNC CORPORATION (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052623-A1 | Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance | STS, PFAS, POLQ | APP 1929/4885HTR2A 1781/4885GRM5 3387/4885 |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | SFXN1, STS, SRM | APP 4459/4885HTR2A 2668/4885GRM5 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.