Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815018 | 0.86 | LTA4H (0.36) | TP53CES2CES1PCSK9GAA | |
| SCHEMBL6268170 | 0.84 | LTA4H (0.37) | TP53CES2CES1PCSK9LTA4H | |
| SCHEMBL31216226 | 0.82 | DNM1 (0.39) | TP53CES2CES1ALDH1A1LTA4H | |
| SCHEMBL8992246 | 0.82 | DNM1 (0.39) | TP53CES2CES1ALDH1A1LTA4H | |
| SCHEMBL12695540 | 0.82 | DNM1 (0.39) | TP53CES2CES1ALDH1A1LTA4H | |
| SCHEMBL8992407 | 0.82 | DNM1 (0.39) | TP53CES2CES1ALDH1A1LTA4H | |
| SCHEMBL2229742 | 0.79 | TP53 (0.39) | TP53PSIP1CES2CES1ALDH1A1 | |
| SCHEMBL9239516 | 0.78 | TDP1 (0.37) | KDM4EALDH1A1GAA | |
| SCHEMBL9746880 | 0.78 | — | — | |
| SCHEMBL415335 | 0.77 | TP53 (0.38) | TP53PSIP1CES2CES1PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |