Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080234 | 0.80 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL10800210 | 0.80 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL28871 | 0.78 | HDAC8 (0.59) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL13832177 | 0.76 | HDAC8 (0.40) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL2010094 | 0.76 | DPP4 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL24017078 | 0.76 | DPP4 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL624888 | 0.76 | PYCR1 (0.42) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL24017079 | 0.76 | DPP4 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL716989 | 0.76 | TSHR (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL721549 | 0.76 | HDAC8 (0.40) | HDAC8CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |