SCHEMBL28871

SCHEMBL28871

C#Cc1ccc(C#C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 4/20 0.59
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA4 P22748 1/20 0.52
KEAP1 Q14145 1/20 0.42
PTPN1 P18031 1/20 0.42
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10481152 0.96 HDAC8 (0.56) HDAC8CA12CA1CA2CA9
Ammonia Solution, Strong SCHEMBL22721248 0.96 HDAC8 (0.56) HDAC8CA12CA1CA2CA9
SCHEMBL139611 0.89 HDAC8 (0.50) HDAC8CA12CA1CA2CA9
SCHEMBL139848 0.89 HDAC8 (0.50) HDAC8CA12CA1CA2CA9
SCHEMBL1306534 0.89 HDAC8 (0.50) HDAC8CA12CA1CA2CA9
Water SCHEMBL11190539 0.86 HDAC8 (0.48) HDAC8CA12CA1CA2CA9
SCHEMBL10481156 0.86 HDAC8 (0.48) HDAC8CA12CA1CA2CA9
SCHEMBL106193 0.83
SCHEMBL121302 0.83
SCHEMBL18894194 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554797-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS Politecnico di Milano (IT) 2025-05-21 EP claimed
US-20250122132-A1 NITRIFICATION INHIBITORS LINCOLN UNIVERSITY (NZ) 2025-04-17 US claimed
US-20240335795-A1 Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method NORTHEAST NORMAL UNIVERSITY (CN) 2024-10-10 US claimed
CN-118161983-A Hollow sphere structure conjugated microporous polymer TiO2Preparation method and application of composite membrane material 西北民族大学 2024-06-11 CN claimed
CN-113735058-B NaAlH with ultrafine carbon holes4Hydrogen storage material and preparation method thereof 滨州学院 2024-05-07 CN claimed
EP-3990417-B1 IMPROVEMENTS IN AND RELATING TO NITRIFICATION INHIBITORS LINCOLN UNIV (NZ) 2024-03-27 EP claimed
CN-117463158-A Method for preparing porous aromatic skeleton membrane based on inorganic salt template method 东北师范大学 2024-01-30 CN claimed
WO-2024013693-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS POLITECNICO DI MILANO (IT) 2024-01-18 WO claimed
CN-117402324-A Method for rapidly synthesizing microporous organic network material by ultrasonic assistance 山东第一医科大学(山东省医学科学院) 2024-01-16 CN claimed
CN-117362889-A Preparation method of modified wave-transparent polyarylacetylene resin and composite material thereof 航天特种材料及工艺技术研究所 2024-01-09 CN claimed
US-4097460-A DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS HERCULES INCORPORATED (US) 1978-06-27 US claimed
US-4070333-A AROMATIZATION CATALYST, ADDITION POLYMERIZATION HERCULES INCORPORATED (US) 1978-01-24 US claimed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-4026860-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US claimed
US-4020265-A Polyacetylene tetrapolymers GENERAL ELECTRIC COMPANY (US) 1977-04-26 US claimed
US-3993711-A THERMOSETTING RESINS; COUPLING AGENTS; CARBOXYLATED PREPOLYMER HERCULES INCORPORATED (US) 1976-11-23 US claimed
US-3933722-A Meet extrudable polyacetylene copolymer blends GENERAL ELECTRIC COMPANY (US) 1976-01-20 US claimed
US-3933957-A Process for producing shaped articles from an acetylenic polymer GENERAL ELECTRIC COMPANY (US) 1976-01-20 US claimed
US-3931093-A CURING HERCULES INCORPORATED (US) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335795-A1 Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method SHROOM3, SIN3A, KCNN2 HDAC8 4327/4885CA12 1548/4885CA1 1936/4885
US-20250122132-A1 NITRIFICATION INHIBITORS NOS1, NOS2, NOS3 HDAC8 1783/4885CA12 2688/4885CA1 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.