Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043822 | 0.95 | PPARG (0.51) | PPARG | |
| SCHEMBL8993065 | 0.94 | PPARG (0.42) | PPARG | |
| SCHEMBL9582592 | 0.92 | PPARG (0.41) | PPARG | |
| SCHEMBL9045308 | 0.91 | ACHE (0.45) | PPARG | |
| SCHEMBL9043551 | 0.89 | ACHE (0.48) | — | |
| SCHEMBL8992556 | 0.87 | PPARG (0.54) | PPARG | |
| SCHEMBL9046073 | 0.85 | ACHE (0.43) | — | |
| SCHEMBL9140447 | 0.85 | PPARG (0.44) | PPARG | |
| SCHEMBL9143126 | 0.84 | ACHE (0.45) | PPARG | |
| SCHEMBL9143603 | 0.84 | ACHE (0.46) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5424316-A | Imidazopyridine derivatives for the treatment of hypertension | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5409936-A | Useful in prophylaxix; exhibits potent angiotensin ii inhibitory acivities | TANABE SEIYAKU CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0531874-A1 | Imidazopyridine derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |