Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796236 | 0.83 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL1508162 | 0.80 | MAOB (0.36) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL5495023 | 0.79 | ATM (0.52) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL6258542 | 0.78 | DRD2 (0.68) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL1508155 | 0.77 | KCNN4 (0.40) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL5857455 | 0.76 | ATM (0.57) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL11712752 | 0.74 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL3979738 | 0.74 | CYP2D6 (0.58) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL651852 | 0.74 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL2066381 | 0.74 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |