Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9867622 | 0.99 | ALDH1A1 (0.49) | ALDH1A1POLBRAB9ALMNAMAPKAPK2 | |
| SCHEMBL10489435 | 0.86 | ALDH1A1 (0.45) | ALDH1A1POLBRAB9ALMNAAOC3 | |
| Hydrochloric Acid SCHEMBL16036141 | 0.83 | ALDH1A1 (0.43) | ALDH1A1POLBRAB9ALMNAAOC3 | |
| SCHEMBL2972263 | 0.81 | RAB9A (0.54) | ALDH1A1POLBRAB9ALMNAMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL9866849 | 0.80 | RAB9A (0.53) | ALDH1A1POLBRAB9ALMNAMAPKAPK2 | |
| SCHEMBL9582051 | 0.80 | RAB9A (0.49) | ALDH1A1POLBRAB9ALMNAAOC3 | |
| Hydrochloric Acid SCHEMBL9214005 | 0.76 | ALDH1A1 (0.47) | ALDH1A1POLBRAB9ALMNAAOC3 | |
| SCHEMBL7218771 | 0.72 | ALDH1A1 (0.37) | ALDH1A1POLBRAB9ALMNAAOC3 | |
| SCHEMBL4004258 | 0.71 | RAB9A (0.56) | ALDH1A1POLBRAB9ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9214874 | 0.71 | RAB9A (0.49) | ALDH1A1POLBRAB9ALMNAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5424316-A | Imidazopyridine derivatives for the treatment of hypertension | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5409936-A | Useful in prophylaxix; exhibits potent angiotensin ii inhibitory acivities | TANABE SEIYAKU CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0531874-A1 | Imidazopyridine derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4999359-A | Analgesics | DR. LO ZAMBELETTI S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |