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SCHEMBL8992682

SCHEMBL8992682

CCCC(Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC6A4 P31645 5/20 0.41
▸ PPARA Q07869 3/20 0.38
▸ SLC6A9 P48067 4/20 0.38
▸ NOS2 P35228 2/20 0.36
▸ HTT P42858 1/20 0.34
▸ PPARG P37231 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4313190 0.79 HTT (0.35) HTT
SCHEMBL8656055 0.76 HTT (0.36) PPARAHTT
SCHEMBL7691328 0.74 HTT (0.34) HTT
SCHEMBL8659939 0.74 HTT (0.34) PPARAHTTPPARG
SCHEMBL5239672 0.74 HTT (0.36) HTT
SCHEMBL4708010 0.73 HTT (0.38) HTT
SCHEMBL8660426 0.72 ALDH1A1 (0.41) HTT
SCHEMBL8408601 0.72 KDM4E (0.41) PPARG
SCHEMBL8657700 0.72 HTT (0.40) HTT
SCHEMBL8407690 0.72 HTT (0.41) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 — — EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 — — WO disclosed