Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704370 | 0.81 | AOC3 (0.40) | HTR2AHRH1KMT2AOPRM1LMNA | |
| SCHEMBL2244555 | 0.80 | HRH1 (0.50) | KCNH2HTR2AHRH1SLC6A4CYP3A4 | |
| SCHEMBL3110907 | 0.79 | SIGMAR1 (0.40) | HTR2AOPRM1LMNASIGMAR1ALDH1A1 | |
| SCHEMBL19470844 | 0.79 | POLB (0.40) | KCNH2HTR2AOPRM1LMNASIGMAR1 | |
| SCHEMBL2242686 | 0.79 | HTR2A (0.40) | KCNH2HTR2AHRH1SLC6A4CYP3A4 | |
| SCHEMBL19470838 | 0.77 | HTR2A (0.41) | KCNH2HTR2AOPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL21630243 | 0.77 | HTR2A (0.56) | KCNH2HTR2AHRH1GRIN1GRIN2A | |
| SCHEMBL19470821 | 0.77 | HTR2A (0.41) | KCNH2HTR2AOPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL19470848 | 0.77 | HTR2A (0.41) | KCNH2HTR2AOPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL19470845 | 0.77 | HTR2A (0.41) | KCNH2HTR2AOPRM1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531948-B1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING (US) | 1996-07-10 | — | — | EP | disclosed |
| EP-0531948-A1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5101055-A | From the corresponding mono- and di-compounds, palladium monoxide catalyst | DOW CORNING CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |